Optimizing Subjective Cognitive Decline to Detect Early Cognitive Dysfunction
نویسندگان
چکیده
منابع مشابه
Subjective Cognitive Decline
Andrea Talesa,∗, Frank Jessenb,c, Christopher Butlerd, Gordon Wilcockd, Judith Phillipse and Tony Bayerf aCollege of Human and Health Sciences, Department of Psychology, Swansea University, Swansea, Wales, UK bDepartment of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany cGerman Center for Neurodegenerative Disorders (DZNE), Germany dNuffield Department of Clinical Neurosci...
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Identification of subjects at the early stages of Alzheimer's disease (AD) is fundamental for drug development and possible intervention or prevention of cognitive decline. The concept of mild cognitive impairment (MCI) evolved during the past two decades to define subjects at the transitional stage between normal aging and dementia. Evidence from cross-sectional and longitudinal studies has sh...
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Background Mild cognitive impairment is considered as the first clinical manifestation of Alzheimer's disease (AD), when the individual exhibits below performance on standardized neuropsychological tests. However, some subjects before having a lower performance on cognitive assessments already have a subjective memory complaint. Objective A review about subjective cognitive decline, the assoc...
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Functional connectivity (FC) alterations represent a key feature in Alzheimer's Disease (AD) and provide a useful tool to characterize and predict the course of the disease. Those alterations have been also described in Mild Cognitive Impairment (MCI), a prodromal stage of AD. There is a growing interest in detecting AD pathology in the brain in the very early stages of the disorder. Subjective...
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Network analysis has been widely used in studying Alzheimer's disease (AD). However, how the white matter network changes in cognitive impaired patients with subjective cognitive decline (SCD) (a symptom emerging during early stage of AD) and amnestic mild cognitive impairment (aMCI) (a pre-dementia stage of AD) is still unclear. Here, structural networks were constructed respectively based on ...
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ژورنال
عنوان ژورنال: Journal of Alzheimer's Disease
سال: 2021
ISSN: 1387-2877,1875-8908
DOI: 10.3233/jad-201322